Two new Pilot Projects have been approved to begin in fall 2022. Acquisition of a BLI Beacon instrument, made possible by a >$1M gift from an anonymous donor, is the centerpiece of a Center for Optofluidic Cell Studies, with Kate Malecek as Director and Pamela Bjorkman as Faculty Advisor. This highly advanced technology will nucleate a collaborative center for single cell technology, to be established in the BI over the next year. And Scott Cushing will lead the assembly of a table-top X-ray Absorption Beamline that will greatly expand capabilities in X-ray absorption spectroscopy for the Caltech community.